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  1. Mitogen-activated protein kinase - Wikipedia

    A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as …

  2. MAP Kinase Pathways - PMC

    Once activated, the MAPK phosphorylates diverse substrates in the cytosol and nucleus to bring about changes in protein function and gene expression that execute the appropriate biological …

  3. MAPK Cell Signaling Pathway | Thermo Fisher Scientific - US

    The MAPK signaling pathway is essential in regulating many cellular processes including inflammation, cell stress response, cell differentiation, cell division, cell proliferation, …

  4. MAPK signaling pathway - Cusabio

    The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration.

  5. MAPK/ERK pathway - Wikipedia

    The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in …

  6. Understanding Map Kinase Function In Cellular Responses

    Apr 7, 2025 · What is the function of mitogen-activated protein kinase? Mitogen-activated protein kinases (MAPKs) are a family of serine/threonine-specific protein kinases that regulate cellular …

  7. A Comprehensive Review on MAPK: A Promising Therapeutic …

    Oct 22, 2021 · The mitogen-activated protein kinase (MAPK) pathway is an important bridge in the switch from extracellular signals to intracellular responses. Alterations of signaling …

  8. Mitogen-Activated Protein Kinase - an overview - ScienceDirect

    Mitogen-activated protein kinase (MAPK) consists of a series of successively acting kinases that function as central regulators of cell growth, differentiation, and transformation.

  9. Activation and Function of the MAPKs and Their Substrates, the MAPK

    MAPK signaling cascades leading to activation of the MAPKAPKs. Mitogens, cytokines, and cellular stresses promote the activation of different MAPK pathways, which in turn …

  10. MAP kinase kinase kinase - Wikipedia

    The p38 MAPK is regulated by MEKK 1-4 and TAO 1/2 families of MAPKKKs and is responsible for inflammation, apoptosis, cell differentiation, and cell cycle regulation.